Coexistence of two sclerotic bone diseases manifesting as spondyloarthropathy: Double trouble

Coexistence of two sclerotic bone diseases manifesting as spondyloarthropathy: Double trouble

Hypoparathyroidism and fluorosis are two distinct sclerotic bone diseases. Both have high BMD but they behave differently. Fluorosis causes secondary hyperparathyroidism and has been reported to cause renal dysfunction. Here we discuss a case that coincidentally had both the disorders and their interaction.

The double trouble of metabolic diseases: the diabetes–cancer link

The recent recognition of the clinical association between type 2 diabetes (T2D) and several types of human cancer has been further highlighted by reports of antidiabetic drugs treating or promoting cancer. At the cellular level, a plethora of molecules operating within distinct signaling pathways suggests cross-talk between the multiple pathways at the interface of the diabetes-cancer link. Ad...

Double reflux: double trouble

Double vision: double trouble.

To cite: Kesav P, Muthu V, Khurana D. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014207347 DESCRIPTION A 43-year-old smoker presented with painless binocular diplopia and numbness in the left frontotemporal region of 4 weeks duration. Physical examination revealed non-tender bony swelling in the left zygomaticotemporal region with posterior cervical lymphade...

Are double translocations double trouble?

Double translocation heterozygotes are rare, but need not necessarily pose more of a counselling problem than single reciprocal translocation heterozygotes. Nine cases of double translocation are presented, together with a review of the few reports published to date. An attempt is made to provide simple counselling guidelines in the assessment of the risk of producing a liveborn abnormal child....